{"id":1733,"date":"2014-02-20T17:56:51","date_gmt":"2014-02-20T22:56:51","guid":{"rendered":"https:\/\/sylviebeljanski.com\/?p=1733"},"modified":"2022-08-18T09:45:25","modified_gmt":"2022-08-18T13:45:25","slug":"pao-pereira","status":"publish","type":"post","link":"https:\/\/sylviebeljanski.com\/fr\/pao-pereira\/","title":{"rendered":"Le Pao pereira"},"content":{"rendered":"

L\u2019usage traditionnel du Pao pereira<\/span><\/h1>\n

\"Pao<\/p>\n

Le Pao pereira<\/i> aussi orthographi\u00e9 Pau pereira<\/i> (Geissospermum Vellosii, ou Geissospermum leave Velloso) est un arbre bien connu,\u00a0originaire d\u2019Am\u00e9rique du Sud . Cet arbre utilis\u00e9 en m\u00e9decine traditionnelle depuis plusieurs si\u00e8cles, est \u00e9galement tr\u00e8s pr\u00e9sent dans la culture populaire sud am\u00e9ricaine.<\/p>\n

Je me suis int\u00e9ress\u00e9e \u00e0 son usage traditionnel, d’apr\u00e8s les documents publi\u00e9s au cours des trois derniers\u00a0si\u00e8cles au Br\u00e9sil, en Bolivie, en Guyane Fran\u00e7aise, mais \u00e9galement en Italie, France et Angleterre.<\/p>\n

Pao pereira\u00a0: Une monographie qui remonte \u00e0 1848<\/span><\/h3>\n

Le 7 d\u00e9cembre 1848, <\/b>Ezequiel Correa Dos Santos pr\u00e9sente sa th\u00e8se \u00e0 la Facult\u00e9 de M\u00e9decine de Rio de Janeiro.<\/p>\n

\"Pao<\/p>\n

Ce document est de nos jours consid\u00e9r\u00e9 comme la premi\u00e8re monographie officielle sur le\u00a0 Geissospermum vellosii (Pao pereira<\/i>). La troisi\u00e8me partie de son \u00e9tude porte sur 21 cas th\u00e9rapeutiques (p. 17 \u201cTherapeutica\u201d). \u00a0Avant d\u2019entrer dans les d\u00e9tails de chaque cas historique, Ezequiel Correa Dos Santos r\u00e9sume son \u00e9tude en indiquant que \u201cL\u2019administration d\u2019\u00e9corce de Pao Pereira fut b\u00e9n\u00e9fique dans les cas d\u2019induration des tissus, de diarrh\u00e9e chronique, d\u2019h\u00e9morrhagie, d\u2019asth\u00e9nie, et d\u2019\u00e9rysip\u00e8le<\/i>\u201d.<\/p>\n

Le sujet est repris en 1879 par le \u00ab\u00a0Medical Times \u00bb (vol. X p. 276 -Philadelphia) qui publie un article de deux pages consacr\u00e9 au Pao pereira<\/i> (Geissospermum vellosii). Apr\u00e8s une description du mode d\u2019extraction de l\u2019alcalo\u00efde pereirina, le Dr Torres Homem, Professeur de M\u00e9decine Clinique \u00e0 l\u2019Acad\u00e9mie de Rio de Janeiro constate\u00a0: \u00ab\u00a0qu\u2019il n\u2019y a pas de m\u00e9decin au Br\u00e9sil qui n\u2019ait obtenu de bons r\u00e9sultats en utilisant cet extrait dans le traitement des fi\u00e8vres intermittentes <\/i>\u00bb.\u00a0Il mentionne en particulier le cas d\u2019une patiente o\u00f9 la quinine ne donnait pas de r\u00e9sultat,\u00a0 mais qui fut gu\u00e9rie grace \u00e0 des bains quotidiens et des prises orales d\u2019extrait d\u2019\u00e9corce de Pao pereira<\/i>.<\/p>\n

Le Pao pereira<\/span> pour \u00ab\u00a0Rester en bonne sant\u00e9\u00a0\u00bb<\/span><\/h3>\n

\u00ab\u00a0Rem\u00e8des anti-malariens en Guyane fran\u00e7aise\u00a0: Connaissance des comportements et des pratiques<\/i>\u201d, Journal d\u2019Ethnopharmacologie [98 (2005) 351-360], publie une \u00e9tude portant sur 117 personnes issues de 5 groupes ethniques et nationalit\u00e9s diff\u00e9rents, et indiquant qu\u2019en Guyane Fran\u00e7aise, un extrait alcoolique de Geissospermum (Pao pereira<\/i>) est bu pr\u00e9ventivement d\u00e8s qu\u2019apparaissent les premi\u00e8res fi\u00e8vres.<\/p>\n

\u201cIl \u00e9tait surprenant de voir que le plus important et renomm\u00e9 des anti malariens d\u2019Amazonie, le Geissospermum spp., \u00e9tait peu employ\u00e9 de fa\u00e7on curative, mais au contraire utilis\u00e9 davantage de fa\u00e7on pr\u00e9ventive\u201d <\/i>(p.358). Selon un questionnaire (p.355) soumis par les auteurs de l\u2019\u00e9tude, le Pao pereira <\/i><\/a>est consomm\u00e9 en priorit\u00e9 pour \u00ab\u00a0rester en bonne sant\u00e9\u00a0<\/i>\u00bb.<\/p>\n

Avec le recul du nombre de cas de malaria, le Geissospermum (Pao Pereira<\/i>) continue d\u2019\u00eatre consid\u00e9r\u00e9 comme tr\u00e8s utile, mais les raisons de son usage ont \u00e9volu\u00e9.<\/p>\n

\u00ab\u00a0Une \u00e9corce pr\u00e9cieuse\u00a0\u00bb du Br\u00e9sil<\/span><\/h3>\n

\"Pao<\/p>\n

La revue br\u00e9silienne de plante m\u00e9dicinale \u201cRevista Da Flora Medicinal<\/i>\u201d (num\u00e9ro 9 sept 1942, Rio de Janeiro), offre une illustration botanique (p.463) et une description de l\u2019arbre (p.464-465).<\/p>\n

L\u2019article pr\u00e9cise que cette \u00ab\u00a0\u00e9corce pr\u00e9cieuse\u00a0<\/i>\u00bb, \u00ab\u00a0d\u2019un des arbres les plus communs et les plus connus au Br\u00e9sil, est \u00e0 disposition de tous les herboristes\u00a0<\/i>\u00bb et conclue \u00ab\u00a0la racine de Pao pereira, est consid\u00e9r\u00e9e comme le meilleur tonic et f\u00e9brifuge de la flore br\u00e9silienne.<\/i>\u00a0\u00bb<\/p>\n

Dans le \u00ab\u00a0<\/b>Livro verde das plantas medicinais e industriais do Brasil\u00a0<\/i>\u00bb, 1965, l\u2019usage th\u00e9rapeutique du Pao pereira <\/i>est d\u00e9crit comme\u00a0: \u201cUn excellent tonique et un rem\u00e8de puissant contre les fi\u00e8vres intermittentes\u00a0<\/i>\u00bb.<\/p>\n

Il est \u00e9galement recommand\u00e9 pour les probl\u00e8mes digestif, le manque d\u2019app\u00e9tit, les douleurs d\u2019estomac et la constipation.<\/p>\n

19\u00e8me si\u00e8cle l\u2019Am\u00e9rique du Nord d\u00e9couvre le Pao Pereira<\/span><\/h3>\n

C\u2019est certainement \u00e0 l\u2019occasion des grandes expositions universelles de la fin du 19eme <\/sup>si\u00e8cle en Europe et en Am\u00e9rique du Nord, que ces continents d\u00e9couvrirent le Pao pereira<\/i> et ses bienfaits.<\/p>\n

Le Pao pereira<\/i> fut pr\u00e9sent\u00e9 lors l\u2019Exposition Universelle de \u00a0Philadelphie\u00a0et inclus dans la brochure: \u201cBr\u00e9sil \u00e0 l\u2019 Exposition Universel de 1876, Philadelphi<\/i>e\u201d \u2013 \u201cMedicinal plants\u201d (p. 61).<\/p>\n

Il est int\u00e9ressant de noter la distinction d\u00e9j\u00e0 faite d\u00e8s 1876 entre le Geissospermum vellosii et une esp\u00e8ce botanique pr\u00e9sentant une vague ressemblance et appel\u00e9e Aspidosperma.<\/p>\n

Le Journal Am\u00e9ricain de Pharmacie de 1895, recommande le Pao pereira<\/i> comme \u00a0tonique et anti-fi\u00e9vreux, notamment pour combattre les fi\u00e8vres p\u00e9riodiques.<\/p>\n

L\u2019index Merck de 1907 signale que les racines de Geissospermum Vellosii (Pao pereira<\/i>) ont des effets anti-p\u00e9ristaltiques \u00a0et anti-fi\u00e8vreux.<\/p>\n

L\u2019Europe s\u2019int\u00e9resse au Pao pereira<\/span><\/h3>\n

\"Pao<\/a>L\u2019Europe s\u2019int\u00e9ressa \u00e9galement assez t\u00f4t au Pao pereira<\/i>, en <\/b>1884, Le \u00ab\u00a0 Medical Times \u00bb de Londres publie\u00a0 dans\u00a0 \u00a0\u00abNotes, Queries and Replies\u00bb (p. 443) un commentaire\u00a0 sign\u00e9 de\u00a0 Richard G. Daunt : \u00ab\u00a0l\u2019efficacit\u00e9 de la\u00a0 pereirine est extraordinaire, et j\u2019ai souvent observ\u00e9 ses succ\u00e8s apr\u00e8s l\u2019\u00e9chec de la quinine<\/i> \u00bb.<\/p>\n

En France la m\u00eame ann\u00e9e, le Dr Tibiri\u00e7a de\u00a0<\/b>L\u2019Union M\u00e9dicale<\/a>\u00a0 \u00e9crit dans \u00ab La revue des journaux\u00a0<\/i>\u00bb (p.429), \u00a0\u00ab\u00a0la Pereirine (extraite de l\u2019\u00e9corce du Pao pereira, Geissospermum leave) est plus efficace que la quinine dont elle double l\u2019action th\u00e9rapeutique en m\u00eame temps qu\u2019elle emp\u00eache les mauvais effets quand elle est pouss\u00e9e \u00e0 une dose \u00e9lev\u00e9e.\u00a0<\/i>\u00bb<\/p>\n

En 1887,\u00a0 en Belgique le Journal de M\u00e9decine, de Chirurgie et de Pharmacologie<\/a> qualifie le Pao pereira<\/i> de \u00ab Nouveau rem\u00e8de<\/i>\u00a0\u00bb dans la note suivante : \u00ab\u00a0l\u2019alcalo\u00efde Pereirine serait sup\u00e9rieur \u00e0 la quinine contre les fi\u00e8vres palud\u00e9ennes. La dose de 2 gr de chlorhydrate est \u00e0 prendre 4 heures avant l\u2019acc\u00e8s\u00a0<\/i>\u00bb.<\/p>\n

In 1933, \u00e0 Milan, Italie, dans le\u00a0\u00ab\u00a0Medicamenta, Guida Teorico-pratica per Sanitari\u00a0<\/i>\u00bb, le Pao pereira<\/i> est list\u00e9 dans le dictionnaire des m\u00e9dicaments\u00a0:<\/p>\n

\u00ab\u00a0Pao-Pereira \u2013 Feuille du Geissospermum Vellosii – Br\u00e9silienne Plante. Fam. Apocinee
\n<\/i>Partie Utilis\u00e9e: L\u2019\u00e9corse
\n<\/i>Principe actif : Geissopermime and Pereirine (alcaloides)
\n<\/i>Utilisation th\u00e9rapeutique : Fortifiant, f\u00e9brifuge
\n<\/i>Pr\u00e9paration pharmaceutique et\u00a0 posologie: Interne D\u00e9coction (30 gr: 1000) \u00e0 boire 1-2 verre\/jour de chlorure de Pereirine (2 gr.)\u00a0<\/i>\u00bb<\/p>\n

Les scientifiques europ\u00e9ens s\u2019int\u00e9ressent d\u00e9sormais \u00e0 analyser ce pr\u00e9cieux produit avec les moyens de la chimie moderne.<\/p>\n

En Belgique, en 1959, Puisieux publie un article sur la nature de quelques uns des alkaloides du geissospermum<\/a> (Pao Pereira<\/i>) (Ann Pharm Fr. \u00a01959 Oct-Dec ; 17:626-33.)
\n<\/span><\/p>\n

Mirko Beljanski et le Pao pereira<\/span><\/h3>\n
\"Mirko<\/a>

Mirko Beljanski \u00a9 La Fondation Beljanski<\/p><\/div>\n

En France, Mirko Beljanski<\/a> (1923-1998, docteur \u00e9s Sciences et chercheur \u00e0 l’institut Pasteur de Paris) fut le premier \u00e0 \u00e9tudier l\u2019action anticanc\u00e9reuse du Geissospermum (Pao pereira<\/i>), avec \u00a0un extrait s\u00e9lectivement efficace \u00e0 l\u2019encontre des cellules canc\u00e9reuses, qui ne p\u00e9n\u00e9trent pas les cellules saines.<\/p>\n

Il publie sur l\u2019effet anticanc\u00e9reux de son extrait de\u00a0Pao pereira<\/i>, qu\u2019il appelle PB-100 (Pao Beljanski 100).<\/p>\n

Plusieurs publications sont consacr\u00e9es \u00e0 l\u2019efficacit\u00e9 et \u00e0 la s\u00e9lectivit\u00e9 d\u2019action de cet extrait.
\n-\u201dPB-100: un inhibiteur puissant et s\u00e9lectif d\u2019homme BCNU multiplication cellulaire glioblastoma r\u00e9sistante Anticancer Res.<\/a>” \u00a0Nov-Dec de 1993 13\u00a0; (6A):2301-8.<\/p>\n

– \u201cThe anticancer agent PB-100 concentrates in the nucleus and nucleoli of human glioblastoma cells but does not enter normal astrocytes.<\/a>\u201d Int J Oncol. 1995 Jul ; 7(1):81-5<\/p>\n

– “The selective anticancer agents PB-100 and BG-8 are active against human melanoma cells, do not affect on-goal malignant fibroblasts.”<\/i>\u00a0<\/a>Int. J. of Oncol. \u00a01996 Jun; 8(6) ; 1143-8.
\n<\/span>
\nEn 1996, le Docteur Marcowith, ami et collaborateur de Mirko Beljanski, d\u00e9c\u00e8de, laissant derri\u00e8re lui des notes sur l\u2019utilisation du Pao pereira<\/i> en m\u00e9decine moderne.\u00a0Ces notes furent publi\u00e9es en fran\u00e7ais dans le livre, \u00ab\u00a0Cancer\u00a0: l\u2019Approche Beljanski<\/a>\u00a0<\/i>\u00bb (\u00e9ditions Tredaniel)\u00a0 puis reprises en anglais dans le livre \u00ab\u00a0Cancer\u2019s cause, Cancer Cure<\/a>\u00a0<\/i>\u00bb de Morton Walker\u00a0(\u00e9ditions Hugo Publishers)<\/p>\n

Sous l’\u00e9gide de la Fondation Beljanski<\/a>, plusieurs publications de diff\u00e9rentes universit\u00e9s ont confirm\u00e9 l\u2019efficacit\u00e9 et l\u2019absence de toxicit\u00e9 de l\u2019extrait de Pao pereira<\/i>\u00a0(tel que pr\u00e9par\u00e9 par Mirko Beljanski et mis \u00e0 disposition par Natural Source International, Ltd.) et la synergie d\u2019action avec diff\u00e9rentes chimioth\u00e9rapies.<\/p>\n

\"Pao<\/a>“B-Carboline Alkaloid-Enriched Extract from the Amazonian Rain Forest Tree Pao Pereira suppresses Prostate Cancer Cells<\/i>” (Journal of Society Integrative Oncology 7 (2) 59-65 (2009) );<\/p>\n

“Inhibition of pancreatic cancer and potentiation of gemcitabine effects by the extracts of Pao Pereira\u00a0<\/i>\u00bb (Department of Pharmacology, Toxicology and Therapeuthics, University of Kansas Medical Center, 2013),
\nOncology Reports vol 30 n\u00b01\u00a0:149-156 (2013)<\/p>\n

\u00ab\u00a0The plant extract of Pao pereira potentiates carboplatin effects against ovarian cancer\u00a0<\/i>\u00bb (Pharmaceutical Biology 2013)\u00a0: DOI\u00a0: 10.3109\/13880209.2013.808232<\/p>\n

\u00ab\u00a0Pao pereira extract suppresses castration-resistant prostate cancer cell growth, survival and invasion through inhibition of NFkB signaling. Integrative Cancer Therapies\u00a0<\/i>\u00bb 1-10 (2013) DOI.1177\/1534735413510557.<\/p>\n","protected":false},"excerpt":{"rendered":"

L\u2019usage traditionnel du Pao pereira Le Pao pereira aussi orthographi\u00e9 Pau pereira (Geissospermum Vellosii, ou Geissospermum leave Velloso) est un arbre bien connu,\u00a0originaire d\u2019Am\u00e9rique du Sud . Cet arbre utilis\u00e9 en m\u00e9decine traditionnelle depuis plusieurs si\u00e8cles, est \u00e9galement tr\u00e8s pr\u00e9sent dans la culture populaire sud am\u00e9ricaine. Je me suis int\u00e9ress\u00e9e \u00e0 son usage traditionnel, d’apr\u00e8s […]<\/p>\n","protected":false},"author":18,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[152],"tags":[],"class_list":["post-1733","post","type-post","status-publish","format-standard","hentry","category-news-fr"],"yoast_head":"\nLe pao pereira de Mikro Beljanski<\/title>\n<meta name=\"description\" content=\"Cet arbre est utilis\u00e9 en m\u00e9decine traditionnelle depuis plusieurs si\u00e8cles, Mirko Beljanski \u00e9tudia l\u2019action anticanc\u00e9reuse du Geissospermum (Pao pereira).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sylviebeljanski.com\/fr\/pao-pereira\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" 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