{"id":894,"date":"2013-03-29T11:29:35","date_gmt":"2013-03-29T15:29:35","guid":{"rendered":"https:\/\/sylviebeljanski.com\/?p=894"},"modified":"2022-04-01T15:48:37","modified_gmt":"2022-04-01T19:48:37","slug":"nouvelle-edition-du-livre-de-mirko-beljanski-the-regulation-of-dna-replication-transcription","status":"publish","type":"post","link":"https:\/\/sylviebeljanski.com\/fr\/nouvelle-edition-du-livre-de-mirko-beljanski-the-regulation-of-dna-replication-transcription\/","title":{"rendered":"Nouvelle \u00e9dition du livre de Mirko Beljanski, “The Regulation of DNA Replication & Transcription”"},"content":{"rendered":"
\"\"<\/a>

2\u00e8me \u00e9dition<\/p><\/div>\n

J\u2019avais l\u2019intention de vous parler des conf\u00e9rences r\u00e9centes auxquelles j\u2019ai particip\u00e9 en Europe, et remercier toutes les personnes qui sont venues manifester leur soutien \u00e0 la poursuite des recherches engag\u00e9es par Mirko Beljanski, mais je viens de recevoir une livraison tr\u00e8s sp\u00e9ciale. Le livre de Mirko Beljanski, “The Regulation of DNA Replication and Transcription” a \u00e9t\u00e9 r\u00e9imprim\u00e9 et les exemplaires ont \u00e9t\u00e9 livr\u00e9s \u00e0 mon bureau, juste \u00e0 temps pour le 30\u00e8me anniversaire de la publication d’origine aux Editions Karger datant de 1983! Cette 3\u00e8me \u00e9dition a \u00e9t\u00e9 publi\u00e9e avec des commentaires et \u00e9vidences scientifiques du Dr Devra Davis, PhD, MPH qui soutiennent les d\u00e9couvertes innovantes de Mirko Beljanski.<\/p>\n

“La m\u00e9decine est une science qui \u00e9volue sans cesse. Les Recherches et les essais cliniques \u00e9largissent nos connaissances, en particulier pour ce qui concerne la compr\u00e9hension des traitements m\u00e9dicamenteux.” Pendant presque 50 ans, Mirko Beljanski, Dr \u00e8s sciences a \u00e9tudi\u00e9 la biologie de l’ADN et l’ARN et fait de nombreuses d\u00e9couvertes, notamment sur la fa\u00e7on dont certains ARN jouent un r\u00f4le dynamique dans la r\u00e9gulation cellulaire.<\/p>\n

Dans la communaut\u00e9 scientifique, au moment de ses d\u00e9couvertes, la diff\u00e9rence entre l’ADN normal et l’ADN canc\u00e9reux \u00e9tait consid\u00e9r\u00e9e comme caus\u00e9e par des mutations, ce qui signifie des alt\u00e9rations de la structure primaire de l’ADN. Cette explication est toujours d’actualit\u00e9, m\u00eame si aujourd’hui on se focalise davantage sur les oncog\u00e8nes, et surtout les proto-oncog\u00e8nes. Mirko Beljanski a pour sa part, d\u00e9montr\u00e9 qu\u2019une diff\u00e9rence fondamentale entre l’ADN normal et l\u2019ADN canc\u00e9reux r\u00e9side dans sa structure secondaire: la double h\u00e9lice de l’ADN canc\u00e9reux est ouvert en permanence, alors que dans l’ADN normal, l\u2019ouverture est beaucoup plus locale et temporaire, juste pour le temps de la r\u00e9plication ou de l’expression du g\u00e8ne.<\/p>\n

\"\"<\/a>

1\u00e8re \u00e9dition<\/p><\/div>\n

La s\u00e9paration des brins, non r\u00e9gul\u00e9e, entra\u00eene une r\u00e9plication et expression des g\u00e8nes excessive, due \u00e0 de nouveaux sites d’initiation plus expos\u00e9s et sources de propri\u00e9t\u00e9s caract\u00e9ristiques de la cellule canc\u00e9reuse : cet ADN a une multiplication accrue avec synth\u00e8se de prot\u00e9ines anormales.<\/p>\n

Ce livre se concentre sur la fa\u00e7on dont l’Epig\u00e9n\u00e9tique est devenu l’un des domaines les plus dynamiques de la science biom\u00e9dicale et met en \u00e9vidence le principe que Beljanski d\u00e9fendait, \u00e0 savoir que \u00ab l\u2019information g\u00e9n\u00e9tique h\u00e9r\u00e9ditaire seule ne peut pas expliquer toutes les caract\u00e9ristiques ph\u00e9notypiques des organismes vivants\u00bb. Les facteurs environnementaux doivent \u00eatre pris en beaucoup plus grande consid\u00e9ration car ils affectent la cellule et induisent des maladies (dont le cancer).<\/p>\n

“Des \u00e9tudes r\u00e9centes confirment la valeur des id\u00e9es et des travaux que Mirko Beljanski a d\u00e9velopp\u00e9 au cours du si\u00e8cle dernier. Les processus fondamentaux de la R\u00e9plication de l’ADN et de la Transcription sont maintenant mieux compris, ce qui permet de contr\u00f4ler l’information g\u00e9n\u00e9tique, savoir si elle est fauss\u00e9e, la r\u00e9parer, la ma\u00eetriser. Comprendre comment le cancer et autres maladies chroniques surviennent \u00e0 la suite d\u2019interactions entre les g\u00e8nes et l\u2019environnement permet de prendre la mesure du r\u00f4le de l\u2019Epig\u00e9n\u00e9tique sur les cellules qui deviennent malignes et donne des armes pour les r\u00e9parer ou \u00e9liminer.”<\/p>\n

Bien que Mirko Beljanski soit d\u00e9c\u00e9d\u00e9 en 1998, son h\u00e9ritage se perp\u00e9tue \u00e0 travers ses recherches, ses enseignements et ses produits. “Ceux qui partagent notre pr\u00e9occupation d’\u00e9laborer de meilleures fa\u00e7ons de traiter le cancer, b\u00e9n\u00e9ficieront de la lecture de ce travail, ainsi que ceux qui sont d\u00e9termin\u00e9s \u00e0 d\u00e9velopper des m\u00e9thodes pour pr\u00e9venir l’apparition de maladies.” – Devra Davis, PhD, MPH.<\/p>\n

\n","protected":false},"excerpt":{"rendered":"

J\u2019avais l\u2019intention de vous parler des conf\u00e9rences r\u00e9centes auxquelles j\u2019ai particip\u00e9 en Europe, et remercier toutes les personnes qui sont venues manifester leur soutien \u00e0 la poursuite des recherches engag\u00e9es par Mirko Beljanski, mais je viens de recevoir une livraison tr\u00e8s sp\u00e9ciale. Le livre de Mirko Beljanski, “The Regulation of DNA Replication and Transcription” a […]<\/p>\n","protected":false},"author":18,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[152],"tags":[],"class_list":["post-894","post","type-post","status-publish","format-standard","hentry","category-news-fr"],"yoast_head":"\nNouvelle \u00e9dition du livre de Mirko Beljanski, "The Regulation of DNA Replication & Transcription" - Sylvie Beljanski<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sylviebeljanski.com\/fr\/nouvelle-edition-du-livre-de-mirko-beljanski-the-regulation-of-dna-replication-transcription\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nouvelle \u00e9dition du livre de Mirko Beljanski, "The Regulation of DNA Replication & Transcription" - Sylvie Beljanski\" \/>\n<meta property=\"og:description\" content=\"J\u2019avais l\u2019intention de vous parler des conf\u00e9rences r\u00e9centes auxquelles j\u2019ai particip\u00e9 en Europe, et remercier toutes les personnes qui sont venues manifester leur soutien \u00e0 la poursuite des recherches engag\u00e9es par Mirko Beljanski, mais je viens de recevoir une livraison tr\u00e8s sp\u00e9ciale. 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